DEAD Box Polypeptide 33 (DDX33)

DEAD Box Polypeptide 33 (DDX33) is a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants. The sequence AAH30017.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.